| Pitching | G | GS | CG | IP | H | R | ER | HR | SH | SF | HP | BB | K | IB | W | L | Pct | Sv | ERA | |
| Saberhagen,Bret | 7 | 7 | 3 | 56.2 | 44 | 19 | 18 | 6 | 1 | 0 | 0 | 11 | 29 | 1 | 4 | - | 2 | 0.667 | 0 | 2.86 |
| Sadecki,Ray* | 12 | 9 | 1 | 60.1 | 62 | 33 | 30 | 6 | 5 | 4 | 1 | 19 | 45 | 2 | 2 | - | 6 | 0.250 | 0 | 4.48 |
| Sadowski,Jim | 1 | 0 | 0 | 1.0 | 2 | 3 | 3 | 0 | 0 | 1 | 0 | 2 | 1 | 0 | 0 | - | 0 | 0.000 | 0 | 27.00 |
| Sanchez,Luis | 14 | 0 | 0 | 16.0 | 14 | 4 | 3 | 0 | 1 | 0 | 2 | 10 | 8 | 2 | 1 | - | 1 | 0.500 | 5 | 1.69 |
| Sanders,Scott | 9 | 0 | 0 | 10.1 | 6 | 3 | 3 | 1 | 0 | 1 | 0 | 1 | 5 | 0 | 1 | - | 1 | 0.500 | 0 | 2.61 |
| Sanderson,Scott | 12 | 10 | 0 | 65.0 | 87 | 57 | 48 | 13 | 2 | 2 | 2 | 25 | 29 | 0 | 2 | - | 4 | 0.333 | 0 | 6.65 |
| Sanford,Jack | 17 | 17 | 8 | 127.0 | 120 | 57 | 54 | 8 | 10 | 8 | 2 | 39 | 65 | 1 | 10 | - | 5 | 0.667 | 0 | 3.83 |
| Santana,Ervin | 7 | 7 | 0 | 45.2 | 51 | 31 | 27 | 2 | 4 | 0 | 3 | 13 | 33 | 1 | 1 | - | 3 | 0.250 | 0 | 5.32 |
| Santana,Johan* | 9 | 9 | 1 | 63.1 | 42 | 18 | 18 | 4 | 1 | 0 | 1 | 18 | 68 | 0 | 5 | - | 0 | 1.000 | 0 | 2.56 |
| Santiago,Jose | 5 | 3 | 0 | 21.2 | 23 | 14 | 14 | 5 | 1 | 0 | 0 | 7 | 30 | 2 | 1 | - | 1 | 0.500 | 0 | 5.82 |
| Saucier,Kevin* | 7 | 0 | 0 | 6.1 | 3 | 1 | 0 | 0 | 1 | 1 | 0 | 2 | 1 | 2 | 0 | - | 0 | 0.000 | 0 | 0.00 |
| Sauerbeck,Scott* | 2 | 0 | 0 | 1.0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | - | 0 | 0.000 | 0 | 0.00 |
| Saunders,Joe* | 3 | 1 | 0 | 11.1 | 11 | 4 | 4 | 2 | 0 | 0 | 0 | 3 | 6 | 0 | 0 | - | 2 | 0.000 | 0 | 3.18 |
| Schilling,Curt | 9 | 9 | 2 | 62.2 | 59 | 31 | 29 | 5 | 4 | 2 | 0 | 21 | 46 | 3 | 3 | - | 3 | 0.500 | 0 | 4.16 |
| Schiraldi,Calvin | 1 | 0 | 0 | 1.0 | 2 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - | 0 | 0.000 | 0 | 9.00 |
| Schmidt,Jason | 5 | 4 | 0 | 22.1 | 36 | 30 | 29 | 3 | 2 | 3 | 0 | 18 | 11 | 3 | 1 | - | 3 | 0.250 | 0 | 11.69 |
| Schoeneweis,Scott* | 4 | 0 | 0 | 3.2 | 5 | 4 | 4 | 0 | 1 | 0 | 0 | 4 | 4 | 3 | 0 | - | 0 | 0.000 | 0 | 9.82 |
| Schueler,Ron | 4 | 0 | 0 | 5.0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10 | 0 | 0 | - | 0 | 0.000 | 0 | 0.00 |
| Schultz,Barney | 5 | 0 | 0 | 8.1 | 4 | 1 | 1 | 1 | 0 | 0 | 0 | 2 | 5 | 0 | 0 | - | 0 | 0.000 | 1 | 1.08 |
| Schwarz,Jeff | 3 | 0 | 0 | 2.1 | 3 | 2 | 2 | 0 | 0 | 0 | 0 | 3 | 4 | 0 | 0 | - | 0 | 0.000 | 0 | 7.71 |
| Scott,Mike | 9 | 9 | 2 | 69.1 | 58 | 16 | 14 | 5 | 2 | 1 | 0 | 11 | 64 | 0 | 4 | - | 3 | 0.571 | 0 | 1.82 |
| Scott,Tim | 7 | 0 | 0 | 9.0 | 8 | 0 | 0 | 0 | 0 | 1 | 0 | 3 | 6 | 1 | 1 | - | 0 | 1.000 | 0 | 0.00 |
| Seay,Bobby* | 20 | 0 | 0 | 12.2 | 16 | 6 | 5 | 0 | 0 | 0 | 0 | 4 | 7 | 1 | 0 | - | 1 | 0.000 | 1 | 3.55 |
| Segui,Diego | 5 | 5 | 2 | 38.0 | 33 | 17 | 15 | 2 | 2 | 0 | 0 | 13 | 22 | 0 | 2 | - | 3 | 0.400 | 0 | 3.55 |
| Sele,Aaron | 8 | 1 | 0 | 20.0 | 21 | 9 | 9 | 0 | 1 | 1 | 2 | 11 | 12 | 3 | 0 | - | 1 | 0.000 | 0 | 4.05 |
| Shantz,Bobby* | 9 | 0 | 0 | 15.0 | 6 | 1 | 1 | 1 | 1 | 0 | 0 | 2 | 21 | 0 | 5 | - | 0 | 1.000 | 2 | 0.60 |
| Shaw,Bob | 22 | 16 | 5 | 123.0 | 147 | 53 | 49 | 7 | 6 | 2 | 2 | 41 | 31 | 4 | 7 | - | 8 | 0.467 | 1 | 3.59 |
| Shaw,Jeff | 13 | 0 | 0 | 11.2 | 10 | 3 | 3 | 1 | 1 | 2 | 1 | 1 | 6 | 0 | 1 | - | 1 | 0.500 | 0 | 2.31 |
| Sheldon,Rollie | 8 | 8 | 2 | 57.0 | 73 | 43 | 39 | 11 | 4 | 4 | 0 | 15 | 22 | 0 | 1 | - | 5 | 0.167 | 0 | 6.16 |
| Sherry,Larry | 12 | 0 | 0 | 16.2 | 14 | 10 | 8 | 2 | 3 | 2 | 0 | 15 | 10 | 2 | 1 | - | 0 | 1.000 | 0 | 4.32 |
| Shields,Scot | 33 | 0 | 0 | 45.1 | 37 | 14 | 10 | 3 | 4 | 4 | 1 | 10 | 42 | 1 | 3 | - | 4 | 0.429 | 2 | 1.99 |
| Shiell,Jason | 3 | 0 | 0 | 1.0 | 4 | 6 | 2 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | - | 1 | 0.000 | 0 | 18.00 |
| Shirley,Steve* | 1 | 0 | 0 | 1.0 | 5 | 7 | 5 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | - | 0 | 0.000 | 0 | 45.00 |
| Show,Eric | 8 | 8 | 1 | 59.0 | 45 | 22 | 15 | 6 | 2 | 3 | 2 | 21 | 38 | 1 | 3 | - | 3 | 0.500 | 0 | 2.29 |
| Shuey,Paul | 14 | 0 | 0 | 14.1 | 8 | 5 | 5 | 1 | 0 | 1 | 0 | 10 | 11 | 0 | 2 | - | 1 | 0.667 | 1 | 3.14 |
| Siebler,Dwight | 7 | 0 | 0 | 7.1 | 16 | 16 | 12 | 2 | 0 | 0 | 0 | 10 | 1 | 0 | 0 | - | 2 | 0.000 | 0 | 14.73 |
| Silva,Carlos | 9 | 9 | 0 | 57.2 | 57 | 30 | 24 | 9 | 2 | 1 | 1 | 12 | 26 | 0 | 2 | - | 2 | 0.500 | 0 | 3.75 |
| Simmons,Curt* | 7 | 7 | 3 | 58.1 | 53 | 21 | 20 | 3 | 4 | 1 | 0 | 10 | 24 | 1 | 5 | - | 0 | 1.000 | 0 | 3.09 |
| Simontacchi,Jason | 6 | 6 | 0 | 36.0 | 46 | 26 | 24 | 8 | 2 | 0 | 0 | 12 | 13 | 3 | 2 | - | 2 | 0.500 | 0 | 6.00 |
| Simpson,Wayne | 8 | 8 | 3 | 61.1 | 40 | 17 | 15 | 2 | 4 | 2 | 0 | 18 | 37 | 0 | 3 | - | 1 | 0.750 | 0 | 2.20 |
| Sisk,Doug | 11 | 0 | 0 | 12.2 | 11 | 10 | 6 | 1 | 2 | 1 | 0 | 13 | 4 | 1 | 0 | - | 2 | 0.000 | 0 | 4.26 |
| Slaton,Jim | 15 | 7 | 0 | 50.1 | 77 | 46 | 45 | 9 | 5 | 2 | 0 | 30 | 22 | 3 | 2 | - | 7 | 0.222 | 0 | 8.05 |
| Smith,David | 15 | 0 | 0 | 10.1 | 3 | 0 | 0 | 0 | 1 | 1 | 0 | 5 | 9 | 1 | 1 | - | 0 | 1.000 | 8 | 0.00 |
| Smith,Jack | 1 | 0 | 0 | 3.0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | - | 0 | 0.000 | 0 | 0.00 |
| Smith,Joe | 6 | 0 | 0 | 4.1 | 3 | 0 | 0 | 0 | 1 | 0 | 2 | 2 | 4 | 1 | 0 | - | 0 | 0.000 | 0 | 0.00 |
| Smith,Lee | 1 | 0 | 0 | 2.0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | - | 0 | 0.000 | 0 | 0.00 |
| Smith,Pete | 1 | 1 | 0 | 4.2 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 4 | 2 | 0 | 0 | - | 0 | 0.000 | 0 | 0.00 |
| Smith,Roy | 8 | 0 | 0 | 19.0 | 14 | 11 | 10 | 4 | 0 | 0 | 1 | 10 | 8 | 1 | 2 | - | 0 | 1.000 | 0 | 4.74 |
| Smoltz,John | 9 | 9 | 3 | 69.2 | 51 | 24 | 22 | 6 | 3 | 0 | 0 | 21 | 66 | 3 | 3 | - | 5 | 0.375 | 0 | 2.84 |
| Snell,Nate | 2 | 0 | 0 | 2.0 | 4 | 2 | 2 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | - | 0 | 0.000 | 0 | 9.00 |
| Solano,Julio | 2 | 0 | 0 | 2.0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | - | 0 | 0.000 | 0 | 4.50 |
| Sosa,Elias | 8 | 0 | 0 | 6.2 | 4 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 5 | 0 | 0 | - | 0 | 0.000 | 6 | 0.00 |
| Sosa,Jorge | 6 | 0 | 0 | 12.2 | 10 | 3 | 3 | 0 | 0 | 0 | 0 | 5 | 6 | 0 | 1 | - | 1 | 0.500 | 0 | 2.13 |
| Spahn,Warren* | 9 | 9 | 9 | 81.0 | 78 | 22 | 21 | 3 | 5 | 3 | 0 | 10 | 50 | 0 | 6 | - | 3 | 0.667 | 0 | 2.33 |
| Sparma,Joe | 14 | 14 | 4 | 97.2 | 80 | 40 | 30 | 5 | 3 | 3 | 3 | 30 | 55 | 2 | 5 | - | 7 | 0.417 | 0 | 2.76 |
| Splittorff,Paul* | 16 | 16 | 3 | 112.2 | 113 | 56 | 53 | 16 | 4 | 2 | 0 | 32 | 45 | 4 | 4 | - | 9 | 0.308 | 0 | 4.23 |
| Sprague,Ed | 9 | 0 | 0 | 11.0 | 10 | 7 | 7 | 0 | 2 | 0 | 2 | 7 | 7 | 0 | 0 | - | 0 | 0.000 | 0 | 5.73 |
| Springer,Dennis | 6 | 0 | 0 | 14.1 | 29 | 27 | 24 | 3 | 2 | 0 | 1 | 11 | 6 | 3 | 0 | - | 0 | 0.000 | 0 | 15.07 |
| Springer,Russ | 12 | 0 | 0 | 12.2 | 13 | 5 | 5 | 1 | 0 | 0 | 0 | 8 | 13 | 0 | 0 | - | 0 | 0.000 | 0 | 3.55 |
| Stafford,Bill | 11 | 8 | 4 | 68.1 | 61 | 28 | 26 | 5 | 10 | 2 | 4 | 21 | 33 | 2 | 4 | - | 4 | 0.500 | 0 | 3.42 |
| Staley,Gerry | 34 | 1 | 1 | 54.1 | 52 | 21 | 19 | 0 | 1 | 6 | 2 | 13 | 27 | 2 | 5 | - | 7 | 0.417 | 11 | 3.15 |
| Stanek,Al* | 3 | 0 | 0 | 3.1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 0 | - | 0 | 0.000 | 0 | 0.00 |
| Stange,Lee | 7 | 7 | 2 | 50.2 | 53 | 24 | 21 | 4 | 4 | 2 | 0 | 11 | 42 | 1 | 3 | - | 2 | 0.600 | 0 | 3.73 |
| Stanka,Joe | 1 | 0 | 0 | 2.1 | 10 | 5 | 5 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | - | 0 | 0.000 | 0 | 19.29 |
| Stanton,Mike* | 7 | 0 | 0 | 8.0 | 8 | 6 | 6 | 1 | 0 | 0 | 0 | 6 | 4 | 0 | 0 | - | 0 | 0.000 | 1 | 6.75 |
| Stechschulte,Gene | 5 | 0 | 0 | 6.2 | 5 | 1 | 1 | 0 | 1 | 0 | 0 | 2 | 3 | 0 | 2 | - | 1 | 0.667 | 0 | 1.35 |
| Steirer,Rick | 3 | 0 | 0 | 6.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | - | 0 | 0.000 | 1 | 0.00 |
| Stephenson,Garrett | 1 | 1 | 0 | 3.0 | 5 | 4 | 4 | 1 | 0 | 0 | 0 | 3 | 1 | 0 | 0 | - | 0 | 0.000 | 0 | 12.00 |
| Stewart,Dave | 19 | 13 | 5 | 100.1 | 78 | 38 | 32 | 4 | 8 | 2 | 4 | 39 | 57 | 2 | 7 | - | 4 | 0.636 | 1 | 2.87 |
| Stieb,Dave | 9 | 9 | 5 | 72.0 | 67 | 30 | 28 | 7 | 4 | 3 | 2 | 21 | 57 | 1 | 5 | - | 4 | 0.556 | 0 | 3.50 |
| Stigman,Dick* | 3 | 0 | 0 | 4.0 | 2 | 2 | 0 | 0 | 1 | 0 | 0 | 1 | 3 | 0 | 0 | - | 0 | 0.000 | 1 | 0.00 |
| Stoddard,Tim | 10 | 0 | 0 | 9.2 | 8 | 4 | 4 | 0 | 1 | 1 | 0 | 6 | 7 | 0 | 1 | - | 2 | 0.333 | 0 | 3.72 |
| Stone,George* | 5 | 5 | 0 | 28.2 | 32 | 17 | 17 | 5 | 1 | 1 | 1 | 10 | 17 | 0 | 2 | - | 3 | 0.400 | 0 | 5.34 |
| Stottlemyre,Mel | 4 | 4 | 3 | 33.0 | 23 | 7 | 7 | 3 | 1 | 1 | 2 | 11 | 21 | 0 | 2 | - | 2 | 0.500 | 0 | 1.91 |
| Straker,Les | 8 | 8 | 0 | 39.1 | 61 | 41 | 40 | 7 | 2 | 3 | 0 | 12 | 9 | 1 | 1 | - | 6 | 0.143 | 0 | 9.15 |
| Suppan,Jeff | 3 | 2 | 0 | 14.2 | 17 | 11 | 9 | 2 | 1 | 0 | 1 | 7 | 14 | 0 | 0 | - | 2 | 0.000 | 0 | 5.52 |
| Sutcliffe,Rick | 4 | 3 | 0 | 21.0 | 16 | 8 | 5 | 2 | 0 | 1 | 1 | 7 | 6 | 0 | 0 | - | 2 | 0.000 | 0 | 2.14 |
| Sutton,Don | 23 | 21 | 5 | 160.1 | 177 | 96 | 89 | 24 | 11 | 4 | 0 | 54 | 119 | 0 | 7 | - | 10 | 0.412 | 0 | 5.00 |