| # | Pitching | G | GS | W | L | Pct | Sv | ERA | CG | IP | H | R | ER | HR | SH | SF | HP | BB | K | IB | ||
| 1 | Carlton,Steve* | 35 | 34 | 17 | - | 12 | 0.586 | 0 | 3.12 | 13 | 257 | 238 | 98 | 89 | 24 | 23 | 5 | 2 | 66 | 167 | 10 | |
| 2 | Palmer,Jim | 21 | 17 | 14 | - | 3 | 0.824 | 0 | 2.74 | 9 | 160.2 | 112 | 59 | 49 | 12 | 7 | 3 | 2 | 72 | 98 | 2 | |
| 2 | Valenzuela,Fernando | 24 | 24 | 14 | - | 7 | 0.667 | 0 | 2.29 | 14 | 212.2 | 172 | 63 | 54 | 8 | 10 | 3 | 0 | 66 | 152 | 6 | |
| 2 | Lemon,Bob | 23 | 23 | 14 | - | 8 | 0.636 | 0 | 3.43 | 14 | 194 | 185 | 88 | 74 | 15 | 22 | 6 | 3 | 83 | 102 | 2 | |
| 2 | Marichal,Juan | 25 | 25 | 14 | - | 10 | 0.583 | 0 | 2.80 | 14 | 205.2 | 164 | 68 | 64 | 22 | 11 | 6 | 1 | 48 | 99 | 9 | |
| 6 | Clemens,Roger | 26 | 26 | 13 | - | 6 | 0.684 | 0 | 3.34 | 4 | 175.1 | 151 | 84 | 65 | 14 | 7 | 6 | 3 | 51 | 128 | 0 | |
| 6 | McNally,Dave* | 23 | 23 | 13 | - | 7 | 0.650 | 0 | 2.57 | 11 | 175 | 144 | 53 | 50 | 15 | 12 | 4 | 2 | 54 | 81 | 2 | |
| 8 | Kaat,Jim* | 28 | 25 | 12 | - | 10 | 0.545 | 0 | 3.31 | 7 | 190.1 | 185 | 75 | 70 | 17 | 20 | 3 | 3 | 50 | 96 | 5 | |
| 8 | Hershiser,Orel | 32 | 32 | 12 | - | 11 | 0.522 | 0 | 3.38 | 6 | 229 | 206 | 104 | 86 | 32 | 16 | 3 | 6 | 71 | 119 | 5 | |
| 8 | Welch,Bob | 30 | 30 | 12 | - | 15 | 0.444 | 0 | 3.43 | 8 | 230.2 | 218 | 98 | 88 | 30 | 7 | 5 | 3 | 66 | 121 | 1 | |
| 8 | Wynn,Early | 36 | 34 | 12 | - | 15 | 0.444 | 0 | 3.55 | 11 | 256.1 | 227 | 109 | 101 | 19 | 22 | 5 | 3 | 94 | 152 | 8 | |
| 8 | Reuss,Jerry* | 38 | 37 | 12 | - | 16 | 0.429 | 0 | 4.36 | 10 | 264 | 314 | 141 | 128 | 26 | 15 | 8 | 0 | 67 | 111 | 10 | |
| 13 | Nagy,Charles | 18 | 18 | 11 | - | 4 | 0.733 | 0 | 2.75 | 1 | 117.2 | 98 | 41 | 36 | 9 | 6 | 2 | 1 | 45 | 70 | 3 | |
| 13 | Feller,Bob | 22 | 22 | 11 | - | 5 | 0.688 | 0 | 3.21 | 11 | 165.2 | 135 | 61 | 59 | 15 | 10 | 5 | 0 | 58 | 114 | 0 | |
| 13 | Pierce,Billy* | 33 | 22 | 11 | - | 7 | 0.611 | 1 | 3.88 | 4 | 167 | 159 | 78 | 72 | 22 | 8 | 3 | 0 | 51 | 85 | 11 | |
| 13 | Martinez,Pedro | 30 | 28 | 11 | - | 11 | 0.500 | 0 | 4.15 | 5 | 186.1 | 155 | 89 | 86 | 17 | 13 | 6 | 12 | 71 | 203 | 7 | |
| 17 | Alexander,Doyle | 13 | 13 | 10 | - | 2 | 0.833 | 0 | 2.94 | 3 | 98 | 90 | 37 | 32 | 8 | 4 | 2 | 2 | 33 | 57 | 1 | |
| 17 | Leonard,Dennis | 20 | 18 | 10 | - | 3 | 0.769 | 0 | 3.45 | 4 | 143.1 | 121 | 60 | 55 | 19 | 6 | 5 | 3 | 55 | 95 | 1 | |
| 17 | Wells,David* | 18 | 18 | 10 | - | 4 | 0.714 | 0 | 3.61 | 4 | 129.2 | 138 | 55 | 52 | 11 | 7 | 5 | 1 | 16 | 46 | 0 | |
| 17 | Sanford,Jack | 17 | 17 | 10 | - | 5 | 0.667 | 0 | 3.83 | 8 | 127 | 120 | 57 | 54 | 8 | 10 | 8 | 2 | 39 | 65 | 1 | |
| 17 | Drysdale,Don | 16 | 16 | 10 | - | 6 | 0.625 | 0 | 3.14 | 7 | 126 | 111 | 56 | 44 | 13 | 10 | 2 | 3 | 26 | 91 | 1 | |
| 17 | Lerch,Randy* | 24 | 21 | 10 | - | 7 | 0.588 | 0 | 3.73 | 5 | 154.1 | 163 | 67 | 64 | 15 | 7 | 3 | 0 | 45 | 85 | 7 | |
| 17 | Gullett,Don* | 35 | 24 | 10 | - | 9 | 0.526 | 3 | 3.50 | 6 | 182.1 | 173 | 74 | 71 | 24 | 12 | 4 | 0 | 47 | 131 | 3 | |
| 17 | Mussina,Mike | 17 | 17 | 9 | - | 6 | 0.600 | 0 | 4.43 | 4 | 122 | 126 | 64 | 60 | 16 | 5 | 1 | 2 | 30 | 83 | 1 | |
| 25 | Gooden,Dwight | 25 | 25 | 9 | - | 10 | 0.474 | 0 | 3.34 | 9 | 186 | 168 | 77 | 69 | 20 | 12 | 4 | 2 | 69 | 157 | 10 | |